Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

The gut microbiome is essential for human health and disease, acting in a symbiotic relationship with its host. In chronic ...

Background Endoscopic procedures are a notable source of medical waste, contributing significantly to environmental pollution. Prior studies report 0.5–3.0 kg of waste per procedure—compared with just ...

A 24-year-old man presented with a 7-year history of recurrent melena, acutely worsening 3 days prior. He had undergone ...

Figure 2 NaBu combined with anti-PD-1 modulates the cytotoxic subpopulation mainly through the GNLY + CD8 + T cell subset to improve immunotherapy. (A) Uniform manifold approximation and projection ...

Li M, Xu C, Shi J, et al.et al Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway.Gut 2018;67:2169–80. This article has been ...

Correspondence to Professor Peter R Gibson, Department of Gastroenterology, Monash University and Alfred Health, Melbourne, VIC 3004, Australia; Peter.gibson{at}monash.edu Reasons behind such ...

A 65-year-old previously well man presented with 3 weeks of generalised abdominal pain and diarrhoea up to three times per day after overseas travel. White cell count (9.6×106/L) and C-reactive ...

Background Complications of endoscopic mucosal resection (EMR) of large colorectal polyps remain a concern. Objective We aimed to compare safety and efficacy of cold EMR (without electrocautery) to ...

Objective Iron-containing micronutrient powders (MNPs) reduce anaemia in African infants, but the current high iron dose (12.5 mg/day) may decrease gut Bifidobacteriaceae and Lactobacillaceae, and ...

Background Despite the long-standing recommendations of high-protein diets for patients with cancer, the precise mechanisms of this dietary approach in benefiting tumour suppression and enhancing ...

2 Utah-Inha DDS & Advanced Therapeutics Research Center, Incheon, Korea (the Republic of) Background Non-variceal upper gastrointestinal bleeding (NVUGIB) remains a major cause of morbidity and ...