aMedical Clinic 1, Department of Gastroenterology, Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany ...

Studies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental ...

aDepartment of Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland bTissue Engineering Research Group, Royal College of Surgeons in ...

Tooth epithelium (cell surface; yellow) and mesenchyme (cell surface; magenta). Proliferating cells (cyan) expand the tissue, generating a mechanical pressure at the tissue center that drives the ...

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children’s in Los Angeles has identified a mechanism by which embryonic cells ...

In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying author responses. [Editors' note: this paper was reviewed by Review Commons.] We would ...

Introduction: The T-box 4 (TBX4) transcription factor is recognized as a risk gene in pulmonary arterial hypertension (PAH). TBX4 is expressed within the lung mesenchyme in the developing lung and is ...

Among the most common human birth defects, orofacial clefts (OFCs) are thought to result from gene–environment interactions. Our work shows that an environmentally sensitive epigenetic mechanism ...

Researchers in the U.S. turned a special type of mouse stem cell into green, glowing lung cells in the lab and now have a limitless supply they can use as a model to study how pulmonary fibrosis and ...

Our editorial process produces two outputs: (i) public reviews designed to be posted alongside the preprint for the benefit of readers; (ii) feedback on the manuscript for the authors, including ...