The cerebral cortex, the brain’s outermost region responsible for higher cognitive functions, depends on a highly ordered, ...

Biochemists at Caltech have identified how viruses have converged on a method for killing bacteria. The researchers have homed in on an underexplored small transporter called MurJ that is a vital part ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

As men age, many quietly lose the Y chromosome in some cells, and scientists now link this hidden change to heart disease, cancer and even shorter lifespans.

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.

Cancer is no longer seen as a single genetic error but as a complex, multi-layered disease shaped by DNA mutations, epigenetic changes and even patterns in medical images. New research at ...

Whenever we need to perform a task, our cells rely on proteins to accomplish the job. Want to move? That’s a job for actin. Want to see? Rhodopsin will help you. Want to smell? That’s what olfactory ...

Why cells grow to just the right size has long baffled scientists. Too small or too large, and cells can trigger serious diseases, but the genetic switch behind this balance has remained elusive. Now, ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Researchers have designed a smart drug that hunts down and breaks a little-known RNA that cancer cells depend on. The drug recognizes a unique fold in the RNA and triggers the cell to destroy it.

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...