Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

A newly discovered molecule disrupts cancer cells’ ability to repair DNA by triggering the breakdown of key proteins. Cancer ...

Learn more about a new experimental procedure that uses cancer cells’ DNA repair system against itself to make drug-resistant ...

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases like skin cancer, cells also have repair mechanisms that can fix ...

When injured, cells have well-regulated responses to promote healing. These include a long-studied self-destruction process that cleans up dead and damaged cells as well as a more recently identified ...

Researchers have captured the most detailed structural images yet of a DNA repair process that helps BRCA-mutated cancer cells survive, revealing how the RAD52 protein and its yeast ancestor Mgm101 ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...