BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Circulation: Arrhythmia and Electrophysiology A specialized journal dedicated to advancing the understanding and management of cardiac arrhythmias and electrophysiology Editor-in-Chief: Paul J. Wang, ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

BACKGROUND: Allograft arteriosclerosis, a significant cause of graft failure, is linked to the formation of tertiary lymphoid organs. T follicular helper (Tfh) cells are a vital subset of helper T ...

Open in Viewer Figure. Ruxolitinib treatment in AFM: clinical timeline and molecular and cellular responses. A, Clinical timeline illustrating ruxolitinib and methylprednisolone administration, ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Li W, Long L, Yang X, Tong Z, Southwood M, King R, Caruso P, Upton PD, Yang P, Bocobo GA, et al. Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice. Am ...

Transcript Dr. Greg Hundley: Welcome listeners to this June 24th issue of Circulation on the Run. And I'm one of your co-hosts, Dr. Greg Hundley, Associate Editor, Director of the Pauley Heart Center ...

We read with great interest the article by Duan et al, 1 which found that BMP9 (bone morphogenetic protein 9) is protectively expressed in humans and mice with myocardial infarction (MI). BMP9 ...

Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean pulmonary arterial pressure >20 mm Hg. Rarely, PH presents as a primary disorder but is more commonly part of ...

eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are ...