Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for potential future treatment strategies.

A research team led by scientists at Queen Mary University of London and University College London (UCL) has found new clues about how the brains of people with Down syndrome develop differently from ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and ...

A research team led by scientists at Queen Mary University of London and University College London (UCL), has found new clues about how the brains of people with Down Syndrome develop differently from ...

As the authors note, Down syndrome offers a rare scientific advantage – because it is caused by a clearly defined genetic change present from conception, researchers can study brain tissue at the very ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and ...

Researchers show two distinct MECP2 mutations in Rett syndrome elevate miRNA-126-3p, lowering ZO-1 and weakening blood-brain ...

Neuroscientists discover that Rett syndrome mutations cause a leaky brain via overexpressed miRNA-126-3p, pointing to a new therapeutic target for vascular repair.

Unlike treatments that focus on removing plaques that have already formed, levetiracetam works differently. It blocks the production of toxic amyloid beta peptides in the first place.

Linsey Vonn's complex tibial fracture from crashing in 2026 Winter Olympics downhill skiing event led to compartment syndrome ...

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises ...