The biguanide metformin (dimethylbiguanide) was initially introduced for the treatment of type 2 diabetes mellitus in the late 1950s. Today, this drug is considered to be the first-choice agent and ...

Warfarin is one of the most widely used drugs in the world for a variety of indications involving the prevention and treatment of thromboembolic phenomena. Even after 60 years of its use, warfarin's ...

Please provide your email address to receive an email when new articles are posted on . One of the most difficult things we ever have to tell a patient is: “You are not a good candidate for LASIK.” ...

Osteoarthritis affects 600 million people worldwide, making it a leading cause of disability. With no disease-modifying treatments available or on the horizon, oral non-steroidal anti-inflammatory ...

Birth Control Pills / Oral Contraceptive Pills are not recommended for women who have had blood clots or heart or kidney or liver problems and it increases the risk for certain cancers. The pill is ...

Appropriate drug prescribing is an ongoing challenge and may at times generate controversy. Whether we have adequate and reliable data to alter our prescribing of the antihyperglycemic agent metformin ...

The absolute contraindications for laparoscopic cholecystectomy from the 1980s (pregnancy, previous abdominal surgery, bowel obstruction, coagulopathy, obesity, cirrhosis, inability to tolerate ...

These specific contraindications cause consternation for clinicians who may wish to prescribe metformin but do not want to put their patients at risk of lactic acidosis or expose themselves to ...

Please provide your email address to receive an email when new articles are posted on . The LLM delivered 94.9% sensitivity and 99.1% specificity. The researchers noted the presence of false positives ...

Tubal Sterilization is indicated when the patient voluntarily requests for a permanent method of contraception. Special legal and ethical criteria must be met in cases where the patient is undergoing ...