Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...
Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...
In their new study, the team looked to see what role this intercellular flow might play in other, noncancerous tissues. "Whether you allow the fluid to flow between cells or not seems to have a major ...
TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...
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Intercellular fluid flow, not just cell structure, governs how tissues respond to physical forces
Now, MIT engineers have found that this "intercellular" fluid plays a major role in how tissues respond when squeezed, pressed, or physically deformed. Their findings could help scientists understand ...
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