New research from the University of Minnesota School of Dentistry and Masonic Cancer Center is providing important new insights into the structure of a human virus that causes blood cancer. In their ...

In order to expand access to cutting-edge research technology, the University of California, Santa Cruz, is welcoming institutions in the United States and abroad to use its powerful ...

The cryogenic electron microscopy (cryo-EM) field exploded in popularity during the 2010s' "resolution revolution." The 2017 Nobel Prize in Chemistry awarded Jacques Dubochet, Joachim Frank, and ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Particles (encircled in green) are spaced at a distance from the noise surrounding the nanobeads (purple), which would otherwise obscure them. Sample loss has been a persistent problem in cryo-EM, a ...

Researchers have identified the first high-resolution experimentally determined structure in proteins that helps them survive harsh conditions such as radiation, heat and even the vacuum of space. A ...

Most people have witnessed -- or rather smelled -- when a protein enzyme called sulfite reductase works its magic. This enzyme catalyzes the chemical reduction of sulfite to hydrogen sulfide. Hydrogen ...

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to ...