During the first 72 hours in particular, extracellular vesicles—nanoparticles enclosed in cell membranes—play a significant role in the embryonic development of zebrafish. This is the result of a ...

Mouse and cell-based studies have shown that macroH2A histone variants predominantly associate with heterochromatin. Functional studies found that macroH2As are involved in gene repression, inhibiting ...

The key to understanding vertebrate development and the origins of human birth defects may lie with the fishes--that is, with the zebrafishes (Danio rerio). Using zebrafish mutants produced primarily ...

Seattle researchers have developed a technique to quantify the changes in gene activity that occur throughout zebrafish embryos in response to specific edits to key genes. The approach makes it ...

An illustration of zebrafish heart development, showing the migration of cells in the growing embryo after 17 hours, 1 day and 2 days to form the heart. Most heart cells come from the embryonic ...

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...