Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have identified a mechanism that protects the female brain from genetic diseases. Although one of the two X chromosomes is ...

X-chromosome inactivation varies across different areas of brains. Here, fluorescent imaging data from a mouse reveal where the father’s X chromosome is most active (white) and least active (blue). A ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the ...

The cells of female mammals randomly inactivate one X chromosome to keep gene dosage the same as in males. Does it matter which X becomes inactive? Surprisingly, it does, according to new research ...

A study in mice suggests how chromosome inactivation may protect girls from a type of autism disorder inherited from their father's X chromosome. Females inherit two copies of the X chromosome, one ...