A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

Six years ago, when Glennis Logsdon was a graduate student, everyone assumed that centromeres had conserved sequences and structures given their essential role in divvying up genetic material. “We had ...

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can “jump around” ...

• The parasitic genus Cuscuta (Convolvulaceae) is exceptional among plants with respect to centromere organization, including both monocentric and holocentric chromosomes, and substantial variation in ...

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...

The use of human artificial chromosomes (HACs) has advanced over the past 25 years. Yet, despite advances in technology to produce and use HACs, there are still many hurdles to overcome before they ...

When a sperm meets an egg, a lot has to go right for an embryo to develop into a complete organism. One critical step of early development is the reorganization of parental DNA to form a new unified ...

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...