A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights ...

Lung cancer in never-smokers exhibits distinct biological characteristics, often leading to late-stage diagnoses due to lack of screening. Targeted therapies, guided by molecular testing, offer ...

KRAS was long thought undruggable in cancer until scientists discovered a hidden binding pocket in mutant KRAS, leading to ...

An expert discusses how long-term safety considerations are evaluated through clinical trial data and postmarketing surveillance, emphasizing the importance of reporting unexpected adverse events to ...

This model illustrates how SETD1B promotes the expansion of H3K4me3 epigenetic marks and upregulates MYC expression, driving cytokine-independent cell growth in FLT3-mutated AML. Acute myeloid ...

Researchers at the University of Southampton have identified a new subtype of lymphoma which could pave the way to improved and more targeted treatments for some blood cancer patients. The cancer ...

Targeted therapy is reaching more patients than ever, but access still depends on factors like cost, insurance coverage, geography, and cancer type. These treatments offer precision and strong ...

Cancer treatment resistance is one of the biggest challenges in cancer care. It occurs when cancer cells adapt to survive despite therapy, making treatments less effective or even completely ...

Every cancer diagnosis begins a deeply personal journey, one shaped by both the disease itself and the individual. Cancer ...

A new personalized pancreatic cancer vaccine is being tested in clinical trials, and a South Carolina doctor says early ...