The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
Research in the last decade has also begun to look at RNA-binding proteins, which control what genes are expressed in health and disease. Two RNA-binding proteins, called LARP4A and LARP4B, which have ...
Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...