Time-resolved cryo-ET uncovered a unified mechanism of synaptic vesicle (SV) exocytosis, reshaping our understanding of brain signaling and disease.

Nervous system functions, from motion to perception to cognition, depend on the active zones of neural circuit connections ...

A research team has resolved a 50-year-old controversy in neuroscience. By employing a self-developed, time-resolved ...

A new study reveals how young synapses gradually mature to send chemical signals correctly — a process that can take days and depends on neural activity.

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

A new type of brain cell, called a glutamatergic astrocyte, has been discovered. It could explain how a variety of neurodegenerative conditions, such as Parkinson’s, develop. Brain cells can largely ...