Researchers have identified a molecular brake that limits DNA replication in healthy cells, revealing how cells prevent a long-suspected replication catastrophe and pointing to a potential ...

DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH When cells in the human body divide, they must first make accurate copies of their DNA. The DNA ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Replicabillity — the ability to obtain the same result when an experiment is repeated — is foundational to science. But in many research fields it has proved difficult to achieve. An important and ...

Back in high school chemistry, I remember waiting with my bench partner for crystals to form on our stick in the cup of blue solution. Other groups around us jumped with joy when their crystals formed ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...