The dementia associated Tau protein — known for its role in microtubule regulation — has now been found to also play important roles in the nerve signaling and mitochondrial function in the brain. A ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells — an achievement that ...

Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...

The decline of brain endothelial cell (BEC) function, due to aging, is a contributor to neurological disease. BECs lining the inner walls of blood vessels regulate the exchange of molecules across the ...

Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

Peptide mapping is an essential step in characterizing, identifying, and monitoring a wide range of properties of target proteins in biotherapeutic studies. Peptide mapping for biotherapeutic proteins ...

When Laurent Cocea lost his job in 2002, he immediately set to work creating his own company to solve a problem he had while still employed at Amgen in Toronto. "We had a team of students who spent ...

For the neurons in the brain to work smoothly and be able to process information, the central nervous system needs a strictly regulated environment. This is maintained by the blood-brain barrier, ...