11C-Methionine positron emission tomography as an early predictor of outcome in bone and soft tissue sarcomas treated by carbon ion radiotherapy No significant financial relationships to disclose.

The nicotinic acetylcholine receptor (AChR) is assembled on the cell surface from multiple subunits produced in the endoplasmic reticulum (ER), but how these mechanisms are controlled has been unclear ...

Novel non-addicting analgetic therapies are urgently needed to reduce the use of opiates as painkillers. With the recent discovery that nicotinic acetylcholine receptors (nAChRs) in the immune system ...

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in ...

A late-stage specialty pharmaceutical company focused on nicotine dependence, with a single lead asset, cytisinicline, being ...

Disturbed transmission via nicotinic acetylcholine receptors in chick fetuses impairs the hatchlings’ preference for animate objects—similar to what is seen in autism spectrum disorder in humans.

Astellas Pharma Inc. has divulged substituted quinolone derivates acting as acetylcholine receptor cluster inducers reported to be useful for the treatment of neuromuscular disorders.

More than 60% of complement inhibitor–naive patients with acetylcholine receptor–positive generalized myasthenia gravis (MG) in diverse clinical populations had a clinically meaningful reduction in MG ...