Nature

Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes

For many years, the t(15;17) has been the karyotypic marker of Acute Promyelocytic Leukemia (APL) (Rowley et al., 1977). The discovery of variant translocations, t(11;17)(q23;q21), t(11;17)(q13;q21), ...
Nature

The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo

Selenium is an essential trace element. Super-nutritional selenium intake has been reported to induce apoptosis through multiple signaling pathways. 6, 7, 8, 9 ...