One in three families knows someone living with memory loss, and late-onset Alzheimer’s disease affects tens of millions worldwide. The strongest common genetic risk factor is APOE: the E4 isoform ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the ...

Researchers have reversed memory loss in aging mice by targeting a protein that builds up in brain cells, pointing toward a potential pathway to counter the cognitive declines of aging. In a new study ...

Scientists have reversed severe memory loss in two mouse models of Alzheimer’s by restoring the brain’s energy supply. Late-stage mice showed brain tissue repairing itself once fuel balance returned, ...

The research found that mice with Alzheimer's disease symptoms improved when a certain brain protein was suppressed.

Shutting down the enzyme PTP1B helps brain immune cells clear plaques again, pointing to a potential new Alzheimer’s ...

A team of researchers at Washington University School of Medicine in St. Louis has found that accelerating the brain’s waste removal system could have tremendous implications for our memory. As ...

Cedars-Sinai researchers created “young” immune cells from human stem cells that reversed cognitive decline and Alzheimer’s symptoms in mice. The treated animals showed better memory and healthier ...

A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain ...

For decades, scientists have looked at various mechanisms responsible for the decline of our mental faculties as we age. A new discovery shows that the accumulation of a certain protein called the ...

Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers boosted lymphatic vessel integrity in old mice and ...