Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...

Theoretical development of a dynamic stiffness matrix (DSM) based direct damping matrix identification method is revisited in this paper. This method was proposed to identify both the mechanism and ...

A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Using a unique stiffness-changing hydrogel system, investigators at the University of California San Diego (UCSD) have uncovered new insights into how the stiffening of breast tissue plays a role in ...

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot ...

(Nanowerk News) Imagine a world inside your body where tiny cells are like workers building and repairing tissue structures. They interact with their surroundings, which include a scaffold called the ...

A preconditioning method for the finite element stiffness matrix is given in this paper. The triangulation is refined in a subregion; the preconditioning process is composed of resolution of two ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...