Simulations detail the mechanisms of kinesins that carry cargo inside cells. Scientists have determined the motor proteins respond best to strong forces and hardly at all to weak ones, even those ...

Crosslinking kinesins support the self-assembly and sliding of parallel or antiparallel microtubules in bundles to develop the bipolar symmetry of the spindle. These kinesins work in large teams, ...

Researchers detail the mechanism that allows propofol, a common anesthetic, to halt the movement of kinesin proteins that deliver cargoes to the far reaches of cells. Like a wrench that gums up the ...

Multiple kinesins are involved in efficient production of male gametes and deletion of kinesin genes halts parasite transmission, a discovery that can be explored further for drug discovery. "In ...

In summary, we have shown that the mechanical activity of biomolecular motors can trigger wear at the molecular scale, which in the context of biological nanosystems requires enhanced self-repair ...

Prospective multicentric trial evaluating prognostic and predictive value of circulating tumor cells in first-line chemotherapy metastatic breast patients. Impact of high-risk classification by FISH ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American It can be hard to visualize how biology works ...

One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...

One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...

If you're the motor protein up front, be prepared to do the heavy pulling. That's one conclusion from a Rice University-led study of the mechanisms that drive kinesins, motor proteins that carry cargo ...