Conversion of IgG antibodies to IgM broadens antibacterial activity

Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can ...
The New England Journal of Medicine

Mucosal IgA against SARS-CoV-2 Omicron Infection

Panel A shows levels of salivary anti–receptor-binding domain (RBD) IgA, secretory immunoglobulin (sIg), IgG, and IgM antibodies after receipt of messenger RNA (mRNA) vaccine (5 to 59 days after each ...
Lupus Science & Medicine

Significant glomerular IgM deposition predicts poorer kidney outcomes in lupus nephritis compared with other forms of immune complex deposits

Objective Glomerular immune complex deposition plays a central role in lupus nephritis (LN), but the prognostic relevance of individual immunoglobulin components remains unclear. This study aimed to ...