The predicted orientation of the Cas9 protein on the AFM substrate is shown, and a simulated AFM image calculated in the scanning view perspective shows remarkable agreement with previous HS-AFM ...
In this interview, News-Medical Life Science talks to Professor Toshio Ando about his interest in high-speed AFM and how it can revolutionize the observation of protein molecules. How did your ...
Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation. Their study, ...
An intrinsic limitation in AFM imaging is that only the surface topography can be acquired, and the AFM tip is too large to resolve details below the nanometer scale. To facilitate the interpretation ...
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate a novel approach for nanoscopic profiling of small extracellular vesicles (sEVs) using high-speed atomic ...
Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and ...
New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques. (Nanowerk News) An enzyme type noted in several ...
Researchers have used high-speed microscopy to investigate native structure and conformational dynamics of hemagglutinin in influenza A. The influenza A viruses, which have instigated deadly pandemics ...
(Nanowerk News) Allowing the direct observation of biomolecules in dynamic action, high-speed AFM has opened a new avenue to dynamic structural biology. An enormous amount of successful applications ...