tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

The number of people using RNA-based therapeutics is set to increase substantially as new drugs reach the market, and companies are looking for ways to scale up RNA production. In September, a team ...

Small ribozymes such as Oryza sativa twister spontaneously cleave their own RNA when the ribozyme folds into its active conformation. The coupling between twister folding and self-cleavage has been ...

Skoltech researchers and their colleagues from the Pasteur Institute and the University of Lorraine, France, have uncovered ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

IGF2BP3 links cancer metabolism and RNA control, offering a potential new therapeutic target for blocking leukemia cell growth.

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of ...