A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...
Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to ...
Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases
The Mount Sinai team focused specifically on class IIa HDACs, which exhibit more tissue-specific functions than class I HDACs, which act more broadly. Among the 18 histone deacetylases discovered to ...
The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region ...
A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.
New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Subscribe to ...
New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...
Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, ...
At least 40 proteins are required for the assembly and function of AMPA receptors, the main neurotransmitter receptors in excitatory synapses of the brain. In the past ten years, Fakler’s research ...
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