Our bodies are composed of many different types of cells that work together to build and maintain normal physiological ...

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...

Much of what we know about biology comes from animal models, particularly mice. Applying these insights to humans, however, ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Researchers say gene switches currently offer limited temporal and spatial precision and can also have adverse effects. Now, a recent study, “Electromagnetic field-inducible in vivo gene switch for ...

Gene expression in eukaryotes is governed not only at the level of transcription but also by tightly regulated steps in the translation of mRNA into protein. Control mechanisms span initiation, ...

A mouse study finds that leukemia inhibitory factor alters the expression of several immune checkpoint-related genes in the ...