Warfarin is one of the most widely used drugs in the world for a variety of indications involving the prevention and treatment of thromboembolic phenomena. Even after 60 years of its use, warfarin's ...

The biguanide metformin (dimethylbiguanide) was initially introduced for the treatment of type 2 diabetes mellitus in the late 1950s. Today, this drug is considered to be the first-choice agent and ...

Please provide your email address to receive an email when new articles are posted on . There are drug-drug interactions between the COVID-19 treatment ritonavir/nirmatrelvir and various classes of ...

Objective: This study investigated the impact of FDA-approved labeling -- ie, precautions and contraindications specified for a drug's use -- on the prescribing of such drug and whether these ...

The absolute contraindications for laparoscopic cholecystectomy from the 1980s (pregnancy, previous abdominal surgery, bowel obstruction, coagulopathy, obesity, cirrhosis, inability to tolerate ...

These specific contraindications cause consternation for clinicians who may wish to prescribe metformin but do not want to put their patients at risk of lactic acidosis or expose themselves to ...