Drug addiction is a chronic, often relapsing disorder that affects millions of people worldwide. Despite successful treatment, many individuals struggle to maintain sobriety and may relapse.

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

In a study that was originally published late last year, researchers unveiled the risks for former cocaine users who may relapse by taking methylphenidate. Methylphenidate is used as a treatment for ...

Neurons in a specific brain circuit regulating mood are stained in green, and the transcription factor DeltaFosB, found in some of these circuit neurons, is labeled in red. When a cocaine addict ...

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

The top Massachusetts court unanimously ruled Monday that a judge can require defendants with substance use disorders to remain drug-free as a condition of probation and send them to jail if they ...

A study in mouse models demonstrates how cocaine alters hippocampal function, driving relapse, and identifies a possible therapeutic target. Researchers at Michigan State University (MI, USA), led by ...

"I don't think I felt happy," Cudi reflects of the "dark" period of his life, which included run-ins with the law and a relapse Michael Loccisano/Getty Kid Cudi is getting real about his journey with ...

What’s the most addictive drug? Newly published research indicates that when focusing on persistent drug memory, craving, and addiction, the most addictive illegal drug is cocaine. In contrast, the ...