Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome.

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

Penn Engineers have developed a new way to use AI to solve inverse partial differential equations (PDEs), a particularly ...

Using an AI-driven approach, researchers found DNA within nucleosomes is often partly exposed, enabling nuanced gene ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

Researchers have discovered that DNA wrapped around nucleosomes exists in multiple partially open states rather than simply ...

Researchers use AI to discover 14 distinct nucleosome states, revealing that DNA packaging acts as a "volume dial" for gene ...