Rather than working on the surface of cells like some cancer medicines, small molecules are able to slip inside the cell to ...

Breast cancer (BRCA) remains the most common malignant cancer in women worldwide. Although a range of treatments exists, ...

A total of 871 patient samples were retrospectively tested using the VENTANA PD-L1 (SP263) assay (Roche Diagnostics, Indianapolis, IN), including 481 enrolled patients and 390 patients who did not ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...

Griffith University researchers have shown that the shape and surface chemistry of microscopic "re-entrant" structures—tiny overhanging caps arranged like mushroom tops—can tune how cancer cells stick ...

Metformin use in mCRC patients improved PFS during first-line 5-fluorouracil-based chemotherapy, but no OS benefit was observed. The study suggests metformin's potential as an adjunct therapy in mCRC, ...

The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the ...

When it comes to their survival, cancer cells have a host of backup plans. This is especially true of the nutrients that cancers use to grow and spread. In addition to relying on sugars like glucose ...

A vigorous workout can spark anti-cancer proteins, cut cancer cell growth, and help survivors fight recurrence by reducing inflammation and improving body composition. Intense exercise sparks ...