A Brossay Lab study reveals how nonclassical CD8+ T cells can be activated by molecules that go undetected by classical CD8+ ...

Powerful white blood cells referred to as CD8 killer T cells enable the body to control infections and fight cancer. But when they become exhausted, they can become dysfunctional and ineffective.

A parasite that may already be hiding in your brain has a shocking survival trick: it can infect the very immune cells sent to destroy it. Yet most people never get sick, and new research from UVA ...

Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

A type of immune cell targeting the Epstein-Barr virus may play a key role in driving multiple sclerosis (MS), a study found.

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

Scientists have discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters ...

Clonally expanded CD8+ T cells are key drivers of alopecia areata, mediating epithelial cell death and immune infiltration. JAK inhibitors are approved for AA treatment, but recurrence is common, ...

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't ...

After months of shrinking scans, the tumors suddenly came roaring back. Oncologists have seen this pattern for years in ...