Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...
Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...
Researchers have resolved a 50-year-old scientific mystery by identifying the molecular mechanism that allows tissues to ...
The use of gene array analysis to determine down-stream molecular expression patterns of trastuzumab (T) treatment No significant financial relationships to disclose. This is an ASCO Meeting Abstract ...
In animals the process of programmed cell death, or apoptosis, is thought to be mediated by caspases, a family of cysteine proteases that cleave one another and key intracellular proteins, killing the ...
Scientists from Stanford University and the University of Texas MD Anderson Cancer Center have discovered a class of molecules that use endogenous proteins to modulate genetic pathways involved in ...
Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age. In a major new ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results