Imagine trying to design a key for a lock that is constantly changing its shape. That is the exact challenge we face in ...

Primary Structure: 100% amino acid sequence identity confirmed between ABP-450 and BOTOX®, based on sequence coverage of 93% - 99% for the five proteins that comprise the 900kD botulinum toxin type A ...

Three-letter DNA “words” can decide whether a yeast cell cranks out a medicine efficiently or sputters along. The words are called codons, and they are the genetic code’s way of spelling out amino ...

While researchers have already succeeded in obtaining sequence information from single DNA strands, a further major challenge in bioanalytics is the direct determination of the amino acid sequence ...

While DNA sequencing is a useful tool for determining what's going on in a cell or a person's body, it only tells part of the story. Protein sequencing could soon give researchers a wider window into ...

Proteins are the workhorses of cells and provide vital insights to cell health and disease function. Immunoassays and mass spectrometry are well established methods for studying proteins and have led ...

Structural disorder is vital for proteins' function in diverse biological processes. It is therefore highly desirable to be able to predict the degree of order and disorder from amino acid sequence.

Amino acid sequencing has become a highly automated and efficient process. It plays an invaluable role in protein biochemistry, and is making an increasing contribution to modern molecular biology and ...

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...