Given the well-precedented use of TMs for Markovnikov-selective nucleophilic alkene functionalization, we proposed that PAr 3-catalysed Markovnikov selectivity could result from a mechanism analogous ...

In this Review we examine a broad spectrum of iron-catalysed alkene difunctionalization reactions, emphasizing their mechanistic diversity and synthetic utility. Each section begins with a conceptual ...

NUS chemists have developed a new "catalyst control" blueprint to overcome a longstanding challenge in the site-selective dicarbofunctionalization of unactivated alkenes, by enabling the reaction to ...

Chemists at the Max-Planck-Institut für Kohlenforschung have developed a practical two-step method for alkylating alkenes via thianthrenation, addressing a long-standing synthetic challenge. This ...

In a development that could revise organic chemistry textbooks, a new catalytic version of alkene dichlorination makes the reaction more versatile. Now, researchers have devised the first catalytic ...

A dilute solution of bromine is added to samples of heptane and cyclohexene. The bromination reactions and mechanisms are compared. UV light splits the bromine molecule into two reactive radicals, ...

Cyclopropanes are a common motif in medicinal chemistry. Three-carbon rings show up in drug structures for conditions including asthma, psoriasis, and COVID-19. But despite its utility, cyclopropane ...