Within germinal centres (GCs), B cells cycle between two zones: the dark zone (DZ) and the light zone (LZ) 3,4,5. In the LZ, B cells compete for limited T follicular helper (T FH) cell help, which ...

Mice adoptively transferred with mouse B cells edited via CRISPR to express human antibody variable chains could help evaluate candidate vaccines and develop better antibody therapies. However, ...

Antibodies play a vital role in the immune system by providing protection against foreign invaders, such as bacteria and viruses. Produced by B cells, antibodies are protein molecules that can be ...

Antibodies are essential for immune defense and safeguarding against bacteria, viruses, and other foreign entities. Produced by B cells, these protein molecules offer the potential for treating ...