Living cells are highly organized, yet they are not assembled using rigid blueprints or by following a predetermined plan.

Understanding how microscopic interactions between proteins in cells produce large-scale organization and asymmetry is a fundamental question in cell biology.

Living cells are highly organized, yet they are not assembled using rigid blueprints or by following a predetermined plan. Instead, order emerges on ...

Smooth muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of physiological functions, including blood pressure regulation and gut peristalsis. The ...

Most of us will probably be able to recall at least vaguely that a molecule called ATP is essential for making our bodies move, but this molecule is only a small part of a much larger system. Although ...

Cell generated force plays essential roles in a wide range of biological processes, such as cell motility, cytokinesis, and tissue morphogenesis. In a study published in Nature Communications, a ...

Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different ...

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological ...