Many genes are of unknown functions in any sequenced genome. A combination of chemical and genetic perturbations has been used to investigate gene functions. Here we present a case that such ...
Figure 1: Structure of human ProRS with bound ligands. Figure 3: HF interacts with both the site for amino acid activation and the site for docking the 3′-end of tRNA. To probe the adenylate-formation ...
The high affinity of Lemna minor glutamine synthetase for ammonium (Kapp m 1.2 - 1.5 x 10-5 M) and its strong inhibition by ADP and 5-AMP contrasts with the low affinity (Kapp m 3 10-2 M) for ammonium ...
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