The Advanced Cell Engineering and 3D Models (ACE-3M) Core provides established services offered previously by AIM and C-BASS cores plus new expanded capabilities for tumor organoids grown in 3D ...

Advanced 3D cell models recreate the complexity of human tissues, enabling researchers to examine tumor progression, probe neurological disorders, and assess therapeutic candidates. By capturing the ...

The development could help scientists develop patient-specific treatments and one day offer a lab-grown lung transplant option.

In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...