Brain goop that traps hunger neurons drives obesity - Nature
WEB1 day ago · The authors fed mice a high-fat, high-sugar diet for 12 weeks and monitored the scaffolding around the hunger neurons by taking tissue samples and monitoring gene activity.
Unveiling the Secrets of the DIO-B6-M Mouse Model for Obesity …
WEBSep 13, 2024 · The inbred strain C57BL/6 mice are widely used to establish diet-induced obesity (DIO) mouse models by feeding them a high-fat diet. Studies have shown that compared to C57BL/6N mice, C57BL/6J mice carry a deletion of exons 7-11 of the Nntgene. The loss of function of this gene can result in mitochondrial metabolic dysfunctionin pancreatic β ...
Optimal fasting duration for mice as assessed by metabolic status
WEB6 days ago · Mouse model. High-fat diet. In the study of obesity and diabetes, mice are widely used for experimental research, and fasting is a common procedure used to reset metabolism in mouse models. The ...
Breakthrough Drug Trial in Mice Reverses Obesity Without …
WEBSep 4, 2023 · Phase 1 clinical trials are showing promising signs for a new drug that successfully reduced weight and fat mass in obese mice on a high-fat diet while not disrupting their appetite.
C57BL/6J substrain differences in response to high-fat diet ...
WEBAug 20, 2020 · C57BL/6J-related mouse strains are widely used animal models for diet-induced obesity (DIO). Multiple vendors breed C57BL/6J-related substrains which may introduce genetic drift and environmental...
Mice Treated with This Cytokine Lose Weight by ‘Sweating’ Fat
WEBJul 29, 2021 · Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls, according to new research published Thursday in Science from researchers in the Perelman School of Medicine at the University of Pennsylvania.
Is it possible to lose weight by 'sweating' fat? - Medical News Today
WEBAug 3, 2021 · Researchers have induced weight loss in obese mice by boosting levels of an immune-signaling molecule or “cytokine.” The fat loss did not result from eating less or faster metabolism but by...
New research uncovers a path to lowering obesity in mice by …
WEBJan 17, 2022 · Blocking the activity of an enzyme inside fat cells can decrease obesity and related health disorders in mice, according to new research led by the University of Michigan Life Sciences Institute.
Foods | Free Full-Text | L-Theanine Ameliorates Obesity-Related
WEB1 day ago · Du Z, Wu G, Cheng H, Han T, Li D, Xie Z. L-Theanine Ameliorates Obesity-Related Complications Induced by High-Fat Diet in Mice: Insights from Transcriptomics and Metabolomics. Foods . 2024; 13(18):2977.
High fat diet induced obesity model using four strains of mice: …
WEBMar 19, 2020 · High fat diet (HFD) treated mouse is widely used as experimental animal model for hyperlipidemia and hyperglycemia study. Many factors contribute to establish animal model that meant to simulate high fat and glucose diet induced phenotypes.
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